Activity

Research into advanced biomaterials for biomedical applications

Regenerative medicine

• Three-dimensional matrices and/or mediums for cell therapy
• Composite materials for tissue regeneration
• Materials for controlled dosage
• Materials and processes for cell preservation

Non-implantable devices, implants, and prostheses

• Development of antimicrobial, osteo-inductive, anti-rejection and anticoagulant materials
• Osteo-integratable materials
• Biotribology
• Shape-memory materials
• Materials for thermal, conductive insulation or impermeable materials

Development of medical devices and biomedical products

• Development of biomedical products in the field of ophthalmology:cornea implants and regenerative medicine
• Development of biomedical products in the field of traumatology and dentistry: bone substitutes
• Development of biomedical products in the cardiovascular field:stents and cardiac valves

CE Marking of Medical Devices

• Biocompatibility trials of chemical and mechanical characterization
• Introduction of the total quality system
• Advice on drawing up the “Technical File” for biomedical products
• Validation of sterilization methods for biomedical products
• Study of the regulations applicable to the different products
• Updating of the state of the technique

Evaluation of In-service Behaviour

• Mechanical behaviour and fatigue resistance. For example, breaking resulting from load demands, etc.
• Resistance to corrosion, leaching, etc.
• Evaluation of design aspects
• Redesign of parts
• Effects of sterilization processes on the material
• Fault analysis

Characterization of products and biomaterials

• Biocompatibility trials
• Toxicity trials
• Conducting of mechanical and fatigue characterization trials
• Chemical characterization and corrosion resistance trials

Advanced technology services

• Advanced techniques in Microscopy, Characterization and Nano-structural Analysis.
• Studies of mechanical properties of surfaces and interphases of biomaterials and materials for medical use.
• Nano-indentation.
• Measurements of finishes and thicknesses of biocompatible layers on a nano-metric level. Nano-profilometry and roughness.
• Chemical and micro-structural analysis of biomaterials and materials for medical use. Raman spectroscopy.
• Chemical and nano-structural analysis of surfaces and boundaries of biomaterials and materials for medical use.
• Analysis of sterilizing and anti-adherent layers and coatings at different depths.
• Photoelectron Spectroscopy (XPS) and AUGER.