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Contamination in laboratory consumables can compromise critical experiments
Learn how TECNALIA guarantees the absence of DNase, RNase, human DNA, PCR inhibitors and endotoxins through rigorous testing.
Why contamination-free consumables matter
Laboratory consumables are essential for molecular biology, forensic analysis, pharmaceutical and biopharmaceutical quality control analysis and clinical research. Even minimal contamination can lead to inaccurate results, wasted resources and compromised scientific integrity. DNase and RNase enzymes degrade nucleic acids, while human DNA, PCR inhibitors and endotoxins interfere with sensitive assays such as PCR or sequencing.
For manufacturers and distributors, ensuring contamination-free products is not only a quality requirement—it is a competitive advantage.
Key contaminants and their impact
DNase and RNase These enzymes degrade DNA and RNA molecules, making them particularly harmful in experiments involving nucleic acid analysis. Their presence can invalidate results and require costly repetition of tests.
Human DNA Human DNA contamination poses a major risk in forensic analysis, where even minimal traces can lead to false positives or misinterpretation of evidence.
Endotoxins Endotoxins, originating from bacterial cell walls, can trigger immune responses in cell cultures and distort experimental outcomes.
PCR inhibitors are organic or inorganic substances found in biological/environmental samples that interfere with the Polymerase Change Reaction (PCR) by blocking the DNA polymerase enzyme, binding to the DNA template, or chelating essential ions like Mg²⁺, leading to failed or reduced nucleic acid amplification and potentially false negative results.
TECNALIA’s rigorous testing approach
At TECNALIA, we perform highly sensitive analyses to certify the absence of DNase, RNase, human DNA, PCR inhibitors and endotoxins in laboratory consumables. Our process includes independent testing using advanced molecular techniques.
These procedures ensure that manufacturers and laboratories receive reliable, contamination-free products that meet the highest quality benchmarks.
Compliance with PAS 377:2023 for forensic applications
For forensic consumables, TECNALIA conducts DNA-free analysis in accordance with PAS 377:2023, the specification for consumables used in evidence collection and processing. This standard is essential for manufacturers of forensic kits and consumables
Benefits for manufacturers and laboratories
- Quality assurance: Test performed using advanced molecular techniques
- Risk reduction: Prevent costly errors and reputational damage
- Market differentiation: Offer certified contamination-free products
- Confidence for researchers: Enable accurate and reproducible results
How to request your analysis
Partner with TECNALIA to certify your consumables. Our genetics laboratory combines expertise, advanced technology and strict protocols to deliver reliable results. Ensure your products meet the highest standards.
Conclusion
Contamination-free consumables are essential for scientific progress and forensic reliability. TECNALIA’s commitment to excellence and compliance with PAS 377:2023 positions us as a trusted partner for manufacturers and laboratories worldwide.
By choosing our services, you guarantee integrity, accuracy and confidence in every experiment.
**This article was written in collaboration with Javier Margareto
