“TECNALIA helps IVF clinics turn complex genetic results into reliable knowledge”
The correct interpretation of results is key in assisted reproduction
In the day-to-day practice of medical centres that specialise in assisted reproduction (IVF clinics), cases of mosaicism, abnormal fertilisation resulting in 1PN or 3PN, low amounts of DNA and diagnostic uncertainty pose an increasing challenge for clinical and laboratory teams.
The correct interpretation of these results is key to making informed decisions that have a direct impact on the success rate of assisted reproduction treatments.
In this context, our Genetics Laboratory offers assisted reproduction clinics advanced genetic support in preimplantation genetic testing (PGT), specifically designed to address these kinds of complex scenarios with a higher level of diagnostic reliability.
We offer preimplantation genetic testing supported by massive high resolution sequencing
- Our service offering next-generation sequencing-based PGT is based on high-throughput mass sequencing technology, which has been experimentally validated in collaboration with clinics and centres with extensive experience in IVF.
- This platform makes it possible to analyse all 24 chromosomes simultaneously in a single test,thereby improving the detection of chromosomal abnormalities and facilitating the identification of patterns consistent with embryonic mosaicism, even when these fall within borderline ranges or give rise to clinical uncertainty.
We offer a comprehensive assessment of each assisted reproduction case
Beyond the technology, what sets us apart is our expertise in genetic testing applied to assisted reproduction.
TECNALIA’s Genetics Laboratory team carries out a comprehensive evaluation of each case, taking technical, biological and clinical factors into account, such as the consistency of the chromosomal profiles obtained and the couple’s reproductive history. This approach makes us a key partner for second opinions on genetic testing in complex PGT cycles.
- As well as PGT for aneuploidies (PGT-A), we offer PGT for monogenic disorders (PGT-M) and combined testing for cases where there is a high risk of passing on hereditary conditions to offspring.
- This capability has allowed IVF clinics to broaden their diagnostic scope and offer their patients a high value-added genetic service, even in situations with a high degree of technical complexity.
Reducing diagnostic uncertainty at IVF clinics
Consequently, TECNALIA’s Genetics Laboratory, which has been accredited as a Genetic Testing Centre by the Basque Government’s Department of Health, has been able to position itself as a technological and scientific partner for IVF clinics that want to reduce diagnostic uncertainty, increase confidence in embryo selection and optimise the clinical outcomes of their assisted reproduction programmes.
TECNALIA helps IVF clinics transform complex genetic results into reliable knowledge that can be put into practice, by providing the necessary assurance during one of the most critical stages of the reproductive process.