We work on Pre-implantation Genetic Diagnosis (PGD), a pre-natal diagnosis method used on embryos generated during in-vitro fertilisation, aimed at preventing genetic and hereditary diseases from being passed on to offspring.
We provide fertility clinics with two types of tests for Pre-implantation Genetic Diagnosis (PGD), using the revolutionary NGS technique:
- Pre-implantation Genetic Screening (PGS) or PGD for aneuploidy (PGDa): it aims to identify alterations in embryo chromosome copy numbers (aneuploidy), which will endanger its viability during the implantation phase and in the early stages of gestation.
- PGD of monogenic diseases (PGDm): it aims to identify genetic alterations that have previously been identified in progenitors in embryos generated during an IVF cycle in order to determine those embryos that are mutation-free and hence prevent the disease from being passed on to offspring.
NGS technology offers the following advantages:
- Enables the simultaneous analysis of the 24 chromosomes with the highest resolution.
- Offers the possibility of carrying out studies into aneuploidy and monogenic diseases (caused by mutations in a single gene) separately or simultaneously in a single analysis.
- Reduced analysis time, becoming much faster and avoiding the need to freeze embryos while waiting for results.
- Enables a high number of samples to be analysed simultaneously.
- Assisted reproduction (IVF) clinics that require pre-implantation genetic diagnosis (PGT-A, PGT-M). In short, IVF centres that seek to offer their patients a high added-value service, increasing the success rate of the process.
Certifications and Accreditations
ENAC/ILAC accredited in compliance with standard UNE-EN ISO/IEC 17025: 2017 for Forensic Analysis Testing no. 4/LE2511
Health Authorisation granted by the Basque Government for the Installation and Operation of the Genetics Laboratory