Laboratory service

Pre-implantation genetic diagnosis (PGD) using NGS

Diagnóstico genético preimplantacional (DGP) por NGS

We work on Pre-implantation Genetic Diagnosis (PGD), a pre-natal diagnosis method used on embryos generated during in-vitro fertilisation, aimed at preventing genetic and hereditary diseases from being passed on to offspring.

We provide fertility clinics with two types of tests for Pre-implantation Genetic Diagnosis (PGD), using the revolutionary NGS technique:

  • Pre-implantation Genetic Screening (PGS) or PGD for aneuploidy (PGDa): it aims to identify alterations in embryo chromosome copy numbers (aneuploidy), which will endanger its viability during the implantation phase and in the early stages of gestation.
  • PGD of monogenic diseases (PGDm): it aims to identify genetic alterations that have previously been identified in progenitors in embryos generated during an IVF cycle in order to determine those embryos that are mutation-free and hence prevent the disease from being passed on to offspring.

NGS technology offers the following advantages:

  • Enables the simultaneous analysis of the 24 chromosomes with the highest resolution.
  • Offers the possibility of carrying out studies into aneuploidy and monogenic diseases (caused by mutations in a single gene) separately or simultaneously in a single analysis.
  • Reduced analysis time, becoming much faster and avoiding the need to freeze embryos while waiting for results.
  • Enables a high number of samples to be analysed simultaneously.

Aimed at:

  • Assisted reproduction (IVF) clinics that require pre-implantation genetic diagnosis (PGT-A, PGT-M). In short, IVF centres that seek to offer their patients a high added-value service, increasing the success rate of the process.

Certifications and Accreditations

ENAC 2511
ENAC/ILAC accredited in compliance with standard UNE-EN ISO/IEC 17025: 2017 for Forensic Analysis Testing no. 4/LE2511
Gobierno Vasco
Health Authorisation granted by the Basque Government for the Installation and Operation of the Genetics Laboratory

Preimplantation Genetic Diagnosis PGD

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Genetic Diagnosis brochure

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